Decrease in cerebral inositols in rats and humans.

نویسندگان

  • R A Moats
  • Y H Lien
  • D Filippi
  • B D Ross
چکیده

Rats with portacaval shunts and humans with hepatic encephalopathy show severe myo-inositol depletion in the brain. The portacaval-shunted rat may therefore be a useful model for the investigation of neurochemical pathways containing myoinositol, which are modulated not only in hepatic encephalopathy but also in diabetes mellitus and Alzheimer's disease.

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عنوان ژورنال:
  • The Biochemical journal

دوره 295 ( Pt 1)  شماره 

صفحات  -

تاریخ انتشار 1993